Study: Spike Protein Inhibits DNA Damage Repair

A Swedish study by Jiang and Mei titled “SARS–CoV–2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro” published 13 October 2021 has found that the COVID spike proteins can cause immunodeficiency.


The entire paper is interesting but the abstract pretty much sums it up:

…we report that the SARS–CoV–2 spike protein significantly inhibits DNA damage repair, which is required for effective V(D)J recombination in adaptive immunity. Mechanistically, we found that the spike protein localizes in the nucleus and inhibits DNA damage repair by impeding key DNA repair protein BRCA1 and 53BP1 recruitment to the damage site. Our findings reveal a potential molecular mechanism by which the spike protein might impede adaptive immunity and underscore the potential side effects of full-length spike-based vaccines.

Spike proteins suspected and found to cause damage is not new; for example, a study from Salk found that the spike proteins alone (and not the full virus) can damage lung tissue.


In any case, that the spike proteins can inhibit DNA damage repair is more serious. Even though the vaccine-induced spike proteins are advertised as harmless, it does beg the question as to if and when these so-called vaccines will lead to diseases like cancer.


SARS–CoV–2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro
Figure 1C: Effect of empty vector (E.V) and SARS–CoV–2 proteins on NHEJ DNA repair. Figure 1E: Effect of E.V and SARS–CoV–2 proteins on HR DNA repair. (The values represent the mean +/- SD from three independent experiments.)

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